What Is Cagrilintide?
Cagrilintide is a synthetic, long-acting analog of the peptide hormone amylin used in laboratory research involving amylin receptor signaling and metabolic pathway biology. The molecule incorporates amino-acid substitutions and acylation that distinguish it from native amylin and contribute to its experimental stability and receptor-interaction profile.
PQRS supplies Cagrilintide strictly as a laboratory research material. It is not intended for human or veterinary use.
Cagrilintide Chemical Structure
Structure Source: PubChem CID 171397054.
2D Molecular Structure
Interactive 3D Structure
Structural Representation: The 2D image and interactive 3D viewer are provided as structural reference materials for laboratory research and molecular identification purposes. The interactive 3D viewer displays Cagrilintide bound to the human amylin 3 receptor (AMY3R), RCSB PDB 9BTW. This experimentally determined cryo-EM structure is shown as a receptor-bound cagrilintide structural reference and does not represent an isolated solution structure or constitute product-specific analytical confirmation.
Research Context
Cagrilintide is characterized as an acylated amylin analog. Laboratory research may use the material to investigate amylin receptor interactions, receptor activation, intracellular signaling, peptide stability, and the molecular consequences of sustained receptor engagement.
The structural modifications present in Cagrilintide are also relevant to studies examining how peptide engineering affects molecular persistence, protein interactions, and receptor-signaling characteristics compared with native peptide systems.
Laboratory Research Applications
- Amylin receptor signaling: Investigation of receptor activation and associated intracellular signaling pathways in controlled experimental systems.
- Peptide structure and stability: Study of how amino-acid substitutions and acylation influence molecular properties and experimental persistence.
- Metabolic pathway research: Examination of amylin-associated biochemical and cellular signaling networks.
- Comparative peptide research: Cagrilintide may be evaluated alongside other research peptides to compare molecular structure, receptor interactions, and signaling characteristics.
Handling and Reconstitution
Handle lyophilized Cagrilintide using appropriate laboratory personal protective equipment and aseptic technique. Store according to the storage conditions specified on the product label and accompanying documentation. When preparation of a research solution is required, use an appropriate laboratory solvent and validated experimental procedure.
Chemical Profile
- Peptide Type: Acylated Amylin Analog
- Molecular Formula: C194H312N54O59S2
- Molecular Weight: 4409 g/mol
- PubChem CID: 171397054
For Research Use Only. Not intended for human or veterinary use.
